WebSep 16, 2024 · Definition / general. Thyroid transcription factor 1, also known as NKX2-1 or thyroid specific enhancer binding protein. Homeodomain containing transcription factor, member of the NKX2 gene … WebJul 1, 2024 · Bile duct cancer is a rare disease in which malignant (cancer) cells form in the bile ducts. Bile duct cancer is also called cholangiocarcinoma. A network of tubes, called ducts, connects the liver, gallbladder, and small intestine. This network begins in the liver where many small ducts collect bile (a fluid made by the liver to break down ...
(PDF) Very Rare Liver Neoplasm: Lymphoepithelioma-Like (LEL ...
WebApr 12, 2024 · Given that the biopsy was positive for CK7 with negative hepatocellular (hepatocyte-specific antigen, arginase, glypican), CDX2, TTF1, and synaptophysin markers, the mass was diagnosed as an intrahepatic cholangiocarcinoma (iCCA). WebThe diagnosis of hepatocellular carcinoma (HCC) remains obscure in some complicated cases. Thyroid transcription factor-1 (TTF-1) was presumed to be helpful in the diagnosis of HCC. This paper aims to study the utility of TTF-1 in the diagnosis and differential … tamarack publick
The role of TTF-1 in differentiating primary and metastatic lung
WebMar 14, 2024 · Cholangiocarcinoma may be asymptomatic in the early stages. Classic symptoms of painless jaundice, weight loss, and abdominal pain usually appear in advanced disease. Liver enzymes, blood levels of carbohydrate antigen (CA) 19-9, carcinoembryonic antigen, CA-125; abdominal ultrasound, abdominal CT/MRI, and endoscopic ultrasound for … Webthe antibody clone, TTF-1 has been reported as negative or infrequently positive in tumors of biliary origin. On the basis of an index case of cholangiocarcinoma expressing TTF-1, we were prompted to study TTF-1 and NapA positivity in cholangiocarcinoma. Archived paraffin-embedded tissue blocks from liver, gallbladder, and pancreato-biliary resections … WebFeb 1, 2014 · Cholangiocarcinoma should be considered in the differential when evaluating a TTF-1-positive tumor of unknown primary. As TTF-1 and NapA are not known for biliary system development or detected in non-neoplastic biliary epithelium, the significance of … tamarack men\u0027s boots