Phospho-slp-76 ser376

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WebMay 2024 - Sep 20241 year 5 months. 1250 S Collegeville Rd, Collegeville, PA 19426. • Demonstrated the in vivo efficacy of various GSK’s proprietary small molecules for their … WebAt MetroWest Medical Center, our Speech-Language Pathology services include treatment, and management in the following areas: Dysarthria: Slurred or misarticulated speech, …

4 FastScan™ Phospho-SLP-76 (Ser376) ELISA Kit (Human …

WebPhospho-SLP-76 (Tyr128) Fluorometric Cell-Based ELISA Kit Detection Target: SLP-76 Reactivity: Human, Mouse, Rat Quantity: 2x96 Wells Supplier Page Sign In or Register to … Webimmunosuppressive environment in the presence of prostaglandin E2 (PGE-2) and are able to selectively inhibit phosphorylation of Ser376 of SLP-76. In addition, in vivo anti-tumor … can acer aspire 5 run games

Purified anti-SLP76 Phospho (Ser376) Antibody - BioLegend

Webhuman phospho-SLP-76 (Ser376) as compared to kit #30794. Background: SH2 domain-containing leukocyte protein of 76 kDa (SLP-76) is a hematopoietic adapter protein that is … WebSLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T … WebThis assay kit contains antibodies which recognize the phospho-Ser376 epitope, and a distal epitope, on SLP-76. The protein detected by this kit corresponds to UniProt ID Q13094. uSLP-76 is also known as lymphocyte cytosolic protein 2. These antibodies recognize SLP-76 of human origin. Other species should be tested on a case-by-case basis. fish checkbook covers

THUNDER™ Phospho-SLP-76 (S376) TR-FRET Cell Signaling …

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WebMouse phospho-SLP-76 (Ser376) control lysate HTRF® This lysate is a component of the mouse phospho-SLP-76 (Ser376) kit. It may be used as a residue specific positive control for mouse SLP-76 phosphorylation. See more Size Cat. number selected : - Quantity Request for quotation Prices may differ between countries. WebLymphocyte cytosolic protein (SLP-76) is required for T-cell activation and has been implicated in a number of signaling pathways. SLP76 is phosphorylated at Ser376 by HPK1, and this phosphorylation leads to a decrease in T-cell receptor signaling. o Description of the LANCE Ultra Assay fish checkerWebNo-wash kit for detection and quantitation of phospho-SLP-76 in cells using AlphaLISA SureFire technology. We are now two standalone organizations Life Sciences & … fish chattahoochee river

"WebPhospho-SLP-76 (Ser376) (E3G9U) XP ® Rabbit mAb recognizes endogenous levels of SLP-76 protein only when phosphorylated at Ser376. Non-specific staining was observed in … " - Phospho-slp-76 ser376

Phospho-slp-76 ser376

Store at 4°C FastScan™ Phospho-SLP-76 - Cell Signaling …

Web(14745) Phospho-SLP-76 (Ser376) (D9D6E) Rabbit mAb Supplier Cell Signaling Technology. Host Rabbit Type Primary Clonality Recombinant (D9D6E) Recombinant Yes Conjugate Unconjugated Target Lymphocyte cytosolic protein 2 (Human) UniProt Q13094 - LCP2_HUMAN. Gene LCP2 Modification WebMonoclonal Antibody for studying SLP76 (Ser376) phosphate. Validated for WB, IP, IHC, IHC, F. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-SLP-76 …

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Web76 kDa (SLP-76) is a hematopoietic adapter protein that is important in multiple biochemical signaling pathways and necessary for T cell development and activation (1). ZAP-70 … WebPhospho-SLP-76 (Ser376) control lysate. This lysate is a component of the phospho-SLP-76 (Ser376) kit. It may be used as a residue specific positive control for SLP-76 phosphorylation. Prices may differ between countries.

Webnm using the FastScan™ Phospho-SLP-76 (Ser376) ELISA Kit (Human Preferred) #25424 is shown in the upper figure. The cor-responding western blots using phospho-SLP-76 (Ser376) antibody (left panel) and SLP-76 antibody (right panel) are shown in the lower figure. After serum starvation, Jurkat cells were either left untreated or treated with 11 ... WebPhospho-SLP-76 (Ser376) Antibody recognizes endogenous levels of SLP-76 protein only when phosphorylated at Ser376. This antibody cross-reacts with a 145 kDa protein of …

WebAs Phospho SLP76 (Ser396) is a readout of T cell activation, it was used to monitor the inhibitory effect of PD-L1 recombinant protein on T cell activation. This assay was performed using the two-plate assay protocol. 400 000 Jurkat cells were plated in 25 µL of complete RPMI culture medium with 10% FBS. WebThis assay kit contains antibodies which recognize the phospho-Ser376 epitope, and a distal epitope, on SLP-76. The protein detected by this kit corresponds to UniProt ID Q13094. …

WebJan 20, 2024 · We report here that SLP76-S376A-expressing mice exhibit normal thymocyte development and no detectable phenotypic alterations in mature T cell subsets or other lymphoid and myeloid cell lineages. Biochemical analyses revealed that mutant T cells were hypersensitive to TCR stimulation.

WebFeb 27, 2024 · Image: ELISA detection of phospho-SLP-76 (Ser376) using a FastScan™ sandwich ELISA kit from Cell Signaling Technology. Treatment efficacy is supported by Western blot analysis. Consider using automation can a ceramic tile floor be paintedWebSLP-76 phosphorylated at Ser376 and another that recognizes an invariant epitope of SLP-76. ... Eu-Ab1 and FR-Ab2 (5 µL) for detection of phospho-SLP-76 (S376). • The plate was incubated at RT for . 18 hours. and the TR-FRET signal . was recorded at 665 and 615 nm (EnVision®; lamp excitation). fish chatugeWebtion of SLP-76 at Ser376, but does not affect the level of total SLP-76 protein. The relationship between lysate protein concentration from untreated and H 2 O -treated Jurkat cells and the absorbance at 450 nm using the FastScan™ Phospho-SLP-76 (Ser376) ELISA Kit #30794 is shown in the upper figure. The corresponding western blots using can acer nitro 5 change keyboard colorWebMitra S, Ghosh B, Gayen N, Roy J, Mandal A. Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. J Biol Chem. 2016;291:24579-24593 pubmed fish cheeks amy tanWeb15 min; green), using Phospho-SLP-76 (Ser376) (E3G9U) XP® Rabbit mAb #76384 (solid lines) or concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (dashed lines). Anti-rabbit IgG (H+L), F(ab') 2 Fragment (Alexa Fluor® 488 Conjugate) #4412 was used as a secondary antibody. Western blot analysis of extracts from Jurkat cells ... fish chattanoogaWebThis SLP-76 (Phospho-Ser376) TR-FRET Assay Kit uses a homogeneous TR-FRET assay method amenable to rapid measurement of phosphorylated protein levels in cells. This SLP-76 (Phospho-Ser376) TR-FRET Assay Kit is robust, with a Z’ value of 0.92, and suitable for screening a large number of samples. fish cheating scandal videoWebListed are ELISA Kits for the detection of SLP76, an alias name of lymphocyte cytosolic protein 2. The human protein, encoded by the gene LCP2, is 533 amino acid residues long and has a mass of 60,188 daltons. This protein is reported to have a cytoplasmic cellular localization. This target may also be known as: 76 kDa tyrosine phosphoprotein ... can acer chromebook run windows 10