Flt3 ligand peprotech

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August undefined, 2024

WebThe human and mouse Flt‑3 Ligand proteins show cross-species activity. Flt-3 Ligand is also structurally related to M-CSF and SCF. Flt-3 Ligand is widely expressed in various human and mouse tissues. It is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts (1, 8). WebPeproGMP Human Flt3-Ligand GMP300-19-50UG 50 μg GMP300-19-100UG 100 μg GMP300-19-1MG 1 mg PeproGMP Human Heregulinb-1 GMP100-03-50UG 50 μg GMP100-03-100UG 100 μg GMP100-03-1MG 1 mg ... Please contact [email protected] for our most up-to-date product list. Note: these …

Rat Flt-3 Ligand (FLT3L) Recombinant Protein, PeproTech®

WebAbstract. FLT3 is a receptor tyrosine kinase (RTK) expressed by immature hematopoietic progenitor cells. The ligand for FLT3 is a transmembrane or soluble protein and is … diatherix swab

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WebMay 10, 2012 · FLT3 phosphorylation was assessed by immunoblotting in cell lysates with antibodies recognizing phosphorylated FLT3 (pFLT3, pY589, or pY591). Numbers under the blot indicate relative phosphorylation of FLT3, normalized to FLT3 amounts and to the value at 2.5 minutes stimulation in the control sh/siRNA-treated cells (1.0). WebWe observed that Grb10 physically associates with FLT3 in response to FLT3-ligand (FL) stimulation through FLT3 phospho-tyrosine 572 and 793 residues and constitutively associates with oncogenic FLT3-ITD. Furthermore endogenous Grb10-FLT3 association was observed in OCI-AML-5 cells. WebDec 11, 2024 · While significant progress has been made in the treatment of acute myeloid leukemia (AML), not all patients can be cured. Mutated in about 1/3 of de novo AML, the FLT3 receptor tyrosine kinase is an attractive target for drug development, activating mutations of the FLT3 map to the juxtamembrane domain (internal tandem duplications, … diatherix specimen

Expression of a recombinant FLT3 ligand and its emtansine …

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WebNov 1, 2000 · Here we describe a flt3-ligand (FL)-dependent BM culture system that generated DCs with more diverse phenotypic characteristics. Murine BM cells cultured at high density in recombinant human FL for 9 days developed into small lymphoid-sized cells, most of which expressed CD11c, CD86, and major histocompatibility complex (MHC) … WebPeproTech fms like tyrosine kinase 3 flt3 ligand Fms Like Tyrosine Kinase 3 Flt3 Ligand, supplied by PeproTech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. citing affidavits blue bookWebDec 13, 2012 · In mice, mammalian target of rapamycin (mTOR) has recently been associated with both TLR9-induced IFN-α production and pDC development. 12, 13 mTOR activation is achieved through phosphatidylinositol 3-kinase (PI3K). 14, 15 PI3K generates 3-phosphorylated inositol lipids, causing activation of downstream signaling resulting in … citing afi

"WebFlt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with … " - Flt3 ligand peprotech

Flt3 ligand peprotech

Web欢迎您访问武汉艾美捷科技有限公司官方网站！ Web本发明一般涉及。更具体地，本发明涉及通过粒子将试^递送到免疫细胞，其中所述试剂包含NF-KB信号转导途径的抑制剂和相当于靶抗原的抗原。本发明的方法和组合物特别用于治疗或预防与靶抗原相关的非所需的免疫应答(包含自身免疫性疾病、变态反应和移植相关疾病)。背景技术NF-kB将信号从细胞 ...

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WebFLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. WebJul 31, 2013 · pDC were cultured at 0.25 × 10 6 cells/mL with TLR7 and TLR9 ligands in RPMI medium supplemented with 10% fetal calf serum, penicillin/streptomycin, l -glutamine, nonessential amino acids, and 20 ng/mL of human recombinant Flt3-ligand (PeproTech). Supernatants were collected after 40 hours and assessed for cytokine production.

WebExpression of the flt3 receptor is primarily restricted among hematopoietic cells to the most primitive progenitor cells. The flt3 ligand is similar to Steel factor in that both proteins … WebFlt-3 ligand as a DC growth factor in mice. Flt-3 ligand (Fms-like tyrosine kinase receptor 3 ligand) stimulates the proliferation of stem and progenitor cells through binding to the Flt …

WebThe flt3 ligand is a member of a small family of growth factors that stimulate the proliferation of hematopoietic cells; other members of this family include Steel factor (also known as mast cell growth factor, stem cell factor, … WebFLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related …

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WebFlt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other … diatherix test panelsWebHumanKine FLT3 Ligand is expressed in human HEK 293 cells as a glycosylated monomer with an apparent molecular mass of 24-30 kDa. HumanKine FLT3 Ligand in human HEK … citing affidavitsWebJan 5, 2016 · Bone marrow-derived pDCs were cultured from the long bones of mice in the presence of 100 ng/ml of murine Flt3 ligand (PeproTech Inc., Rocky Hill, NJ) as described previously 24). RPMI 1640 (Sigma-Aldrich, St. Louis, MO) supplemented with 10% FBS (JRH Bioscience, Lenexa, KS), 2-ME (100 μM), penicillin (5 U/ml) and streptomycin (50 … diather lipidproWebOct 8, 2009 · To prepare FLT3-DCs, bone marrow cells were cultured in RPMI 1640 medium supplemented with 10% FBS, 50 μM 2-mercaptoethanol, 10 mM HEPES, pH 7.4, and 100 ng ml −1 human FLT3 ligand (Peprotech) for 8 days. 293T cells were obtained from the American Type Culture Collection (ATCC) and were maintained in DMEM … diathermanous meaningWebAccession Number: P49771 Description: Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation.FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the … diatherix supply order formWebRecombinant Rat EGF EGF является мощным фактором роста, который стимулирует пролиферацию различных citing a filmWebRecombinant Murine Flt3-Ligand 250-31L-10ug from PeproTech Biocompare: The Buyer's Guide for Life Scientists. diatherm carat