Cyp2b10 gene card
WebDec 26, 2014 · Reported Gene symbol Gene name KO WT Up-regulated Ces2a carboxylesterase 2 a 2.493 2.038 Cyp2b13 cytochrome P450 family 2, subfamily b, polypeptide 13 4.695 22.644 WebEthanol-induced Hepatic Cyp2b10 Expression Is Regulated by PPAR / -dependent Modulation of SP1 Activity—Because the previous results indicate that ethanol-induced Cyp2b10 expression was not mediated by CAR activation, functional mapping of the 5 upstream region of the Cyp2b10 gene was performed to identify important regulators …
Cyp2b10 gene card
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WebHuman diseases caused by Cyp2b10 mutations The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in … WebFeb 17, 2003 · The CYP2B10 mRNA is expressed in the lungs of both wild-type and CAR-null mice, and is not induced by PB treatment (Fig. 3). Thus, CAR does not regulate the constitutive expression of the Cyp2b10 gene in mouse lung. Whether CAR regulates the Cyp2b10 expression in mouse intestine remains to be investigated. Download : …
WebUse Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed. Cyp2b10 - … WebMar 21, 2024 · UGT2B10 (UDP Glucuronosyltransferase Family 2 Member B10) is a Protein Coding gene. Diseases associated with UGT2B10 include Crigler-Najjar Syndrome, …
WebJun 1, 2024 · The expression of Cyp2b10, Cyp3a11, Gadd45b and Cyp1a1 genes was analyzed in DAS treated and vehicle treated mice livers. The same RNA samples treated … WebA distal gene fragment, at about -2000 kb in CYP2B1, CYP2B2, and Cyp2b10, has been shown to be a phenobarbital-responsive enhancer independent of proximal promoter …
WebThe nuclear receptor constitutive active/androstane receptor (CAR) is sequestered in the cytoplasm of liver cells before its activation by therapeutic drugs and xenobiotics such as phenobarbital (PB) and 1,4-Bis [2- (3,5-dichloropyridyloxy)]benzene (TCPOBOP) in mouse liver, the regulatory mechanism of which remains poorly understood.
WebCyp2b10cytochrome P450, family 2, subfamily b, polypeptide 10 [ Mus musculus(house mouse) ] Gene ID: 13088, updated on 26-Sep-2024 Download Datasets Gene … fnb of omaha visaWebMar 5, 2024 · Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 [ (house mouse)] Gene ID: 13088, updated on 5-Mar-2024 Summary Predicted to enable heat … fnb of ottawaWebApr 19, 2024 · When gene expression patterns were examined in liver, induction of Cyp2b10 and UGT1A1 gene expression was absent in hUGT1/Car −/− mice, confirming the role of CAR in activation of these genes ... fnb of pa addressWebRNA Gene: 19: GC11P057712: 0.49: 12: AHR: Aryl Hydrocarbon Receptor: Protein Coding: P35869: 54: GC07P016916: 0.44: 13: ABCC3: ATP Binding Cassette Subfamily C … greentech safety awardWebOct 19, 2000 · Here we show that the nuclear receptor CAR mediates the response evoked by a class of xenobiotics known as the ‘phenobarbital-like inducers’. The strong activation of Cyp2b10 gene expression ... fnbo fort collinsWebOn the other hand, progesterone and androgens repressed NR1 activity in HepG2 cells, and the repressed NR1 activity was fully restored by estradiol. Moreover, estrogen treatment elicited nuclear accumulation of CAR in the mouse livers, as well as primary hepatocytes, and induced the endogenous Cyp2b10 gene. greentech sacramento caWebThe constitutive androstane receptor ( CAR) also known as nuclear receptor subfamily 1, group I, member 3 is a protein that in humans is encoded by the NR1I3 gene. [5] CAR is a member of the nuclear … greentech resurfacing